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Arabinoxylan fibre improves metabolic control in people with Type 2 diabetes

Lu, Z, Walker, K, Muir, J and O'Dea, K (2004). Arabinoxylan fibre improves metabolic control in people with Type 2 diabetes. European Journal of Clinical Nutrition,58:621-628.

Document type: Journal Article
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Title Arabinoxylan fibre improves metabolic control in people with Type 2 diabetes
Author Lu, Z
Walker, K
Muir, J
O'Dea, K
Journal Name European Journal of Clinical Nutrition
Publication Date 2004
Volume Number 58
ISSN 0954-3007   (check CDU catalogue open catalogue search in new window)
Start Page 621
End Page 628
Place of Publication United Kingdom
Publisher Nature Publishing Group
HERDC Category C1 - Journal Article (DEST)
Abstract Objective: To determine whether diet supplementation with arabinoxylan-rich (AX)-fibre from wheat improves glycaemic control in Type II diabetes. Design: Randomized, crossover intervention trial. Setting: Monash Medical Centre. Subjects: A total of 15 subjects with Type II diabetes. Interventions: Over two 5-week periods, subjects supplemented their usual diet with control bread and muffins (50% whole wheat, 50% white flour) (control diet) or with AX-bread and muffins (50% whole wheat, 36% white flour, 14% AX fibre) (AX diet). Subjects completed a 7-day food diary. At 0 and 5 weeks, venous blood was collected for determination of fasting and 2 h glucose, insulin, fructosamine and blood lipids. Blood pressure, body weight and body fat were also determined. A 24 h faecal sample, from 12 subjects, was weighed and analysed for faecal polysaccharide as a marker for dietary compliance. Results: Control and AX diets were similar except the AX diet supplied an additional 15.1 (12.0–18.5) (mean (95% confidence intervals)) g/day dietary fibre (P=0.000). Consumption of the AX diet increased faecal output by 61.5 (0.2–122.8) g/day (P=0.05) on a wet weight basis and significantly lowered fasting and 2 h plasma glucose, 2 h insulin and serum fructosamine (P=0.002, 0.000, 0.015, and 0.02, respectively). Blood lipids, body weight, fat mass and blood pressure remained unchanged. Conclusions: A supplement of 15 g/day of AX-rich fibre can significantly improve glycaemic control in people with Type II diabetes.
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Created: Fri, 12 Sep 2008, 08:35:25 CST by Administrator