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Acute rheumatic fever

Carapetis, Jonathan R., McDonald, Malcolm I. and Wilson, Nigel J. (2005). Acute rheumatic fever. The Lancet,366(9480):155-168.

Document type: Journal Article
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Title Acute rheumatic fever
Author Carapetis, Jonathan R.
McDonald, Malcolm I.
Wilson, Nigel J.
Journal Name The Lancet
Publication Date 2005
Volume Number 366
Issue Number 9480
ISSN 0140-6736   (check CDU catalogue open catalogue search in new window)
Start Page 155
End Page 168
Place of Publication United Kingdom
Publisher The Lancet Publishing Group
HERDC Category C1 - Journal Article (DEST)
Abstract Acute rheumatic fever (ARF) and its chronic sequela, rheumatic heart disease (RHD), have become rare in most affluent populations, but remain unchecked in developing countries and in some poor, mainly indigenous populations in wealthy countries. More than a century of research, mainly in North America and Europe, has improved our understanding of ARF and RHD. However, whether traditional views need to be updated in view of the epidemiological shift of the past 50 years is still to be established, and improved data from developing countries are needed. Doctors who work in populations with a high incidence of ARF are adapting existing diagnostic guidelines to increase their sensitivity. Group A streptococcal vaccines are still years away from being available and, even if the obstacles of serotype coverage and safety can be overcome, their cost could make them inaccessible to the populations that need them most. New approaches to primary prevention are needed given the limitations of primary prophylaxis as a population-based strategy. The most effective approach for control of ARF and RHD is secondary prophylaxis, which is best delivered as part of a coordinated control programme.
Keywords acute
Acute Disease
Australia
Child
Children
chronic
Developing Countries
diagnosis
Disease
Epidemiology
fever
group
Health
Heart
Humans
Incidence
Indigenous
Population
Prevalence
prevention & control
primary
Research
review
rheumatic fever
Rheumatic Heart Disease
therapy
university
Vaccine
Vaccines
WHO
DOI http://dx.doi.org/10.1016/S0140-6736(05)66874-2   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)
 
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