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Leanness and type 2 diabetes in a population of indigenous Australians

Brimblecombe, Julie K., Mackerras, Dorothy, Garnggulkpuy, Joanne, Maypilama, Elaine, Bundhala, Leanne, Dhurrkay, Roslyn G., Fitz, Joseph, Maple-Brown, Louise J., Shemesh, Tomer and O'Dea, Kerin (2006). Leanness and type 2 diabetes in a population of indigenous Australians. Diabetes Research and Clinical Practice,72(1):93-99.

Document type: Journal Article
Citation counts: Scopus Citation Count Cited 13 times in Scopus Article | Citations

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IRMA ID 10137xPUB8
Title Leanness and type 2 diabetes in a population of indigenous Australians
Author Brimblecombe, Julie K.
Mackerras, Dorothy
Garnggulkpuy, Joanne
Maypilama, Elaine
Bundhala, Leanne
Dhurrkay, Roslyn G.
Fitz, Joseph
Maple-Brown, Louise J.
Shemesh, Tomer
O'Dea, Kerin
Journal Name Diabetes Research and Clinical Practice
Publication Date 2006
Volume Number 72
Issue Number 1
ISSN 0168-8227   (check CDU catalogue open catalogue search in new window)
Scopus ID 2-s2.0-33645324732
Start Page 93
End Page 99
Total Pages 7
Place of Publication Ireland
Publisher Elsevier Science
HERDC Category C1 - Journal Article (DEST)
Abstract Objective: To determine the prevalence of type 2 diabetes and its risk factors in a population of indigenous Australians. Research design and methods: A cross-sectional study of 332 indigenous community residents aged 15 years and over with fasting blood samples and anthropometric measurements. Results: Almost half of the study population (47.3%) was extremely lean (BMI < 22 kg/m(2)). Leanness was particularly pronounced in the youngest age group (15 < 20 years), 78% of which had a BMI < 22 kg/m(2). The prevalence of diabetes was 12%. It was highest in those 45-54 years and declined in older aged people. No cases of diabetes were detected in those aged less than 30 years. Diabetes prevalence was strongly linked to BMI and age (age-adjusted odds ratio = 24.1, 95% CI 6.0-96.5, p < 0.001) for BMI >= 25 kg/m(2) versus BMI < 22 kg/m(2). Those with the lowest diabetes risk profile are lean (BMI < 22 kg/m(2)) and/or young (age 15-34 years). Conclusions: These results highlight that strategies to prevent or delay the onset of diabetes should focus on the maintenance of leanness from adolescence and throughout adult life whilst young people are still in the process of forming lifelong habits.
Keywords type 2 diabetes
insulin resistance
community intervention
isolated aboriginal community
impaired glucose-tolerance
coronary heart-disease
northern australia
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Created: Fri, 12 Sep 2008, 08:35:25 CST by Administrator