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Indirect effects of childhood pneumococcal vaccination on pneumococcal carriage among adults and older children in Australian Aboriginal communities

Mackenzie, Grant A., Carapetis, Jonathan R., Leach, Amanda J., Hare, Kim M. and Morris, Peter S. (2007). Indirect effects of childhood pneumococcal vaccination on pneumococcal carriage among adults and older children in Australian Aboriginal communities. Vaccine,25(13):2428-2433.

Document type: Journal Article
Citation counts: Scopus Citation Count Cited 9 times in Scopus Article | Citations

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IRMA ID 10414xPUB56
Title Indirect effects of childhood pneumococcal vaccination on pneumococcal carriage among adults and older children in Australian Aboriginal communities
Author Mackenzie, Grant A.
Carapetis, Jonathan R.
Leach, Amanda J.
Hare, Kim M.
Morris, Peter S.
Journal Name Vaccine
Publication Date 2007
Volume Number 25
Issue Number 13
ISSN 0264-410X   (check CDU catalogue  open catalogue search in new window)
Scopus ID 2-s2.0-33847661945
Start Page 2428
End Page 2433
Total Pages 6
Place of Publication UK
Publisher Elsevier
Field of Research 0605 - Microbiology
0799 - Other Agricultural and Veterinary Sciences
1108 - Medical Microbiology
HERDC Category C1 - Journal Article (DEST)
Abstract Nasopharyngeal carriage of Streptococcus pneumoniae in unimmunised adults and older children in three remote Australian Aboriginal communities was compared in 2002 and 2004. Universal childhood pneumococcal vaccination with a catch-up program was introduced in late 2001. Carriage prevalence across all age groups of pneumococcal serotypes included in the 7-valent vaccine was 10% in both 2002 and 2004 (12 and 30 months after introduction of vaccination). This carriage prevalence was lower than anticipated. It is likely that indirect effects of childhood vaccination occurred before the 2002 survey. To further assess indirect effects on carriage of childhood pneumococcal vaccination, data prior to 2002 are required. Between 12 and 30 months following introduction of conjugate pneumococcal vaccination, indirect effects on carriage were unchanged.
Keywords indirect effects
pneumococcal vaccines
bacterial colonisation
DOI http://dx.doi.org/10.1016/j.vaccine.2006.09.015   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)
 
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