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Molecular characterisation of pneumococcal serotype 16F: Established predominant carriage and otitis media serotype in the 7vPCV era

Marsh, Robyn L., Smith-Vaughan, Heidi C., Beissbarth, Jemima, Hare, Kim M., Kennedy, M., Wigger, Christine, Mellon, Gabrielle, Stubbs, Elizabeth, Gadil, J., Pettit, A., Mackenzie, Grant A., Tipakalippa, Priscilla, Morris, Peter S. and Leach, Amanda J. (2007). Molecular characterisation of pneumococcal serotype 16F: Established predominant carriage and otitis media serotype in the 7vPCV era. Vaccine,25(13):2434-2436.

Document type: Journal Article
Citation counts: Scopus Citation Count Cited 8 times in Scopus Article | Citations

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IRMA ID 10014xPUB17
Title Molecular characterisation of pneumococcal serotype 16F: Established predominant carriage and otitis media serotype in the 7vPCV era
Author Marsh, Robyn L.
Smith-Vaughan, Heidi C.
Beissbarth, Jemima
Hare, Kim M.
Kennedy, M.
Wigger, Christine
Mellon, Gabrielle
Stubbs, Elizabeth
Gadil, J.
Pettit, A.
Mackenzie, Grant A.
Tipakalippa, Priscilla
Morris, Peter S.
Leach, Amanda J.
Journal Name Vaccine
Publication Date 2007
Volume Number 25
Issue Number 13
ISSN 0264-410X   (check CDU catalogue  open catalogue search in new window)
Scopus ID 2-s2.0-33847676777
Start Page 2434
End Page 2436
Total Pages 3
Place of Publication UK
Publisher Elsevier Ltd
Field of Research 0605 - Microbiology
0799 - Other Agricultural and Veterinary Sciences
1107 - Immunology
HERDC Category C1 - Journal Article (DEST)
Abstract Young Australian Aboriginal children in remote communities experience very high rates of pneumococcal carriage and otitis media. Prior to introduction of the 7-valent pneumococcal conjugate vaccine (7vPCV, Prevenar), serotype 16F was an important type found in nasal and ear discharge swabs. Since commencement of pneumococcal immunisation for Aboriginal infants in 2001, 16F has become the predominant established serotype in carriage and otitis media in young Aboriginal children. BOX typing and multi-locus sequence typing revealed a diverse population of serotype 16F strains, and evidence of potential capsule switching from a vaccine serotype 4 to a serotype 16F.
Keywords Pneumococcus
Prevenar vaccine
7vPCV
Carriage
DOI http://dx.doi.org/10.1016/j.vaccine.2006.09.016   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)
 
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