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High burden of invasive beta-haemolytic streptococcal infections in Fiji

Steer, A. C., Jenney, A. J. W., Oppedisano, F., Batzloff, M. R., Hartas, J., Passmore, J., Russell, F. M., Kado, J. H. H. and Carapetis, Jonathan R. (2008). High burden of invasive beta-haemolytic streptococcal infections in Fiji. Epidemiology and Infection,136(5):621-627.

Document type: Journal Article
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IRMA ID 10414xPUB53
Title High burden of invasive beta-haemolytic streptococcal infections in Fiji
Author Steer, A. C.
Jenney, A. J. W.
Oppedisano, F.
Batzloff, M. R.
Hartas, J.
Passmore, J.
Russell, F. M.
Kado, J. H. H.
Carapetis, Jonathan R.
Journal Name Epidemiology and Infection
Publication Date 2008
Volume Number 136
Issue Number 5
ISSN 0950-2688   (check CDU catalogue open catalogue search in new window)
Start Page 621
End Page 627
Total Pages 7
Place of Publication Cambride, U.K
Publisher Cambridge University Press
Field of Research 0605 - Microbiology
0799 - Other Agricultural and Veterinary Sciences
1108 - Medical Microbiology
HERDC Category C1 - Journal Article (DEST)
Abstract We undertook a 5-year retrospective study of group A streptococcal (GAS) bacteraemia in Fiji, supplemented by a 9-month detailed retrospective study of β-haemolytic streptococcal (BHS) infections. The all-age incidence of GAS bacteraemia over 5 years was 11.6/100 000. Indigenous Fijians were 4.7 times more likely to present with invasive BHS disease than people of other ethnicities, and 6.4 times more likely than Indo-Fijians. The case-fatality rate for invasive BHS infections was 28%. emm-typing was performed on 23 isolates: 17 different emm-types were found, and the emm-type profile was different from that found in industrialized nations. These data support the contentions that elevated rates of invasive BHS and GAS infections are widespread in developing countries, and that the profile of invasive organisms in these settings reflects a wide diversity of emm-types and a paucity of types typically found in industrialized countries.
DOI http://dx.doi.org/10.1017/S095026880700917X   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)


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