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Influenza vaccine for children and adults with bronchiectasis (Review)

Chang, Christina C., Morris, Peter S. and Chang, Anne B. (2007). Influenza vaccine for children and adults with bronchiectasis (Review). Cochrane Database of Systematic Reviews,2007(3 - Article No. CD006218).

Document type: Journal Article
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Title Influenza vaccine for children and adults with bronchiectasis (Review)
Author Chang, Christina C.
Morris, Peter S.
Chang, Anne B.
Journal Name Cochrane Database of Systematic Reviews
Publication Date 2007
Volume Number 2007
Issue Number 3 - Article No. CD006218
ISSN 1469-493X   (check CDU catalogue open catalogue search in new window)
Total Pages 12
Place of Publication United Kingdom
Publisher John Wiley & Sons. Ltd.
HERDC Category C1 - Journal Article (DEST)
Abstract Background
Bronchiectasis is a major cause of respiratory morbidity especially in developing countries. In affluent countries, bronchiectasis is increasingly recognised in certain subsections of communities (e.g. Aboriginal communities) as well as a coexistent disease/comorbidity and disease modifier in respiratory diseases such as COPD (reported rates of 29-50% in adults). Respiratory exacerbations in people with bronchiectasis are associated with reduced quality of life, accelerated pulmonary decline, hospitalisation and even death. Current recommendations for inactivated influenza vaccination includes adults aged 65 years and over, those in residential care and health care workers and also all adults and children with chronic illness, particularly cardiac and pulmonary diseases.


To evaluate the effectiveness of influenza vaccine as routine management in children and adults with bronchiectasis in (a) reducing the severity and frequency of respiratory exacerbations and (b) pulmonary decline

Search methods

The Cochrane Register of Controlled Trials (CENTRAL), the Cochrane Airways Group Specialised Register, MEDLINE and EMBASE databases were searched by the Cochrane Airways Group. Pharmaceutical manufacturers of influenza were also contacted. The latest searches were performed in July 2006.

Selection criteria

All randomised controlled trials with at least one annual influenza vaccine involving children or adults with bronchiectasis.

Data collection and analysis

Results of searches were reviewed against pre-determined criteria for inclusion. It was planned that two independent reviewers selected, extracted and assessed data for inclusion.

Main results

No eligible trials were identified and thus no data were available for analysis.

Authors' conclusions

There is neither evidence for, nor against, routine annual influenza vaccination for children and adults with bronchiectasis.
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