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The global burden of group A streptococcal diseases

Carapetis, Jonathan R., Steer, Andrew C., Mulholland, E. Kim and Weber, Martin (2005). The global burden of group A streptococcal diseases. Lancet Infectious Diseases,5(11):685-694.

Document type: Journal Article
Citation counts: Altmetric Score Altmetric Score is 67
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IRMA ID 10414xPUB50
Title The global burden of group A streptococcal diseases
Author Carapetis, Jonathan R.
Steer, Andrew C.
Mulholland, E. Kim
Weber, Martin
Journal Name Lancet Infectious Diseases
Publication Date 2005
Volume Number 5
Issue Number 11
ISSN 1473-3099   (check CDU catalogue open catalogue search in new window)
Start Page 685
End Page 694
Total Pages 10
Place of Publication UK
Publisher Lancet Publishing Group
Field of Research 0605 - Microbiology
1103 - Clinical Sciences
1108 - Medical Microbiology
HERDC Category C1 - Journal Article (DEST)
Abstract The global burden of disease caused by group A streptococcus (GAS) is not known. We review recent population-based data to estimate the burden of GAS diseases and highlight deficiencies in the available data. We estimate that there are at least 517,000 deaths each year due to severe GAS diseases (eg, acute rheumatic fever, rheumatic heart disease, post-streptococcal glomerulonephritis, and invasive infections). The prevalence of severe GAS disease is at least 18.1 million cases, with 1.78 million new cases each year. The greatest burden is due to rheumatic heart disease, with a prevalence of at least 15.6 million cases, with 282,000 new cases and 233,000 deaths each year. The burden of invasive GAS diseases is unexpectedly high, with at least 663,000 new cases and 163,000 deaths each year. In addition, there are more than 111 million prevalent cases of GAS pyoderma, and over 616 million incident cases per year of GAS pharyngitis. Epidemiological data from developing countries for most diseases is poor. On a global scale, GAS is an important cause of morbidity and mortality. These data emphasise the need to reinforce current control strategies, develop new primary prevention strategies, and collect better data from developing countries.
Keywords Australia
Developing Countries
rheumatic fever
Rheumatic Heart Disease
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Created: Mon, 26 Nov 2007, 15:07:47 CST