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Case-control study of the association between kava use and pneumonia in eastern Arnhem Land Aboriginal communities (Northern Territory, Australia)

Clough, Alan R., Wang, Zhiqiang, Bailie, Ross S., Burns, Chris B. and Currie, Bart J. (2003). Case-control study of the association between kava use and pneumonia in eastern Arnhem Land Aboriginal communities (Northern Territory, Australia). Epidemiology and Infection,131(1):627-635.

Document type: Journal Article
Citation counts: Scopus Citation Count Cited 6 times in Scopus Article | Citations

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Title Case-control study of the association between kava use and pneumonia in eastern Arnhem Land Aboriginal communities (Northern Territory, Australia)
Author Clough, Alan R.
Wang, Zhiqiang
Bailie, Ross S.
Burns, Chris B.
Currie, Bart J.
Journal Name Epidemiology and Infection
Publication Date 2003
Volume Number 131
Issue Number 1
ISSN 0950-2688   (check CDU catalogue  open catalogue search in new window)
Scopus ID 2-s2.0-0041353511
Start Page 627
End Page 635
Total Pages 9
Place of Publication Cambridge, U.K
Publisher Cambridge University Press
Field of Research 0605 - Microbiology
0799 - Other Agricultural and Veterinary Sciences
1107 - Immunology
HERDC Category C1 - Journal Article (DEST)
Abstract Pneumonia causes significant morbidity and mortality in Aboriginal populations in Australia's Northern Territory (NT). Kava, consumed in Arnhem Land since 1982, may be a risk factor for infectious disease including pneumonia. A case-control study (n=115 cases; n=415 controls) was conducted in 7001 Aboriginal people (4217 over 15 years). Odds ratios (OR) were calculated by conditional logistic regression with substance use and social factors as confounders. Pneumonia, vas not associated with kava use. Crude OR=1.26 (0.74-2.14, P=0.386), increased after controlling for confounders (OR=1.98, 0.63-6.23, P=0.237) but was not significant. Adjusted OR for pneumonia cases involving kava and alcohol users was 1.19 (0.39-3.62, P=0.756). In communities with longer kava-using histories, adjusted OR was 2.19 (0.67-7.14, P=0.187). There was no kava dose-response relationship. Crude ORs for associations between pneumonia and cannabis use (OR=2.27, 1.18-4.37, P=0.014) and alcohol use (OR=1.95, 1.07-3.53, P=0.026) were statistically significant and approached significance for petrol sniffing (OR=1.98, 0.99-3.95, P=0.056).
DOI http://dx.doi.org/10.1017/S0950268803008628   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)


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