Charles Darwin University

CDU eSpace
Institutional Repository

 
CDU Staff and Student only
 

Risk factors associated with typhoid fever in children aged 2-16 years in Karachi, Pakistan

Khan, M. I., Ochiai, R. L., Soofi, S. B., von Seidlein, Lorenz, Khan, M. J., Sahito, S. M., Habib, M. A., Puri, M. K., Park, J. K., You, Y. A., Ali, M., Nizami, S. Q., Acosta, C. J., Bradley-Sack, R., Clemens, J. D. and Bhutta, Z. A. (2012). Risk factors associated with typhoid fever in children aged 2-16 years in Karachi, Pakistan. Epidemiology and Infection,140(4):665-672.

Document type: Journal Article
Citation counts:
Google Scholar Search Google Scholar
Attached Files (Some files may be inaccessible until you login with your CDU eSpace credentials)
Name Description MIMEType Size Downloads
Download this reading vonSeidlein_38009.pdf Published version application/pdf 156.44KB 131
Reading the attached file works best in Firefox, Chrome and IE 9 or later.

IRMA ID kmckayxPUB54
Title Risk factors associated with typhoid fever in children aged 2-16 years in Karachi, Pakistan
Author Khan, M. I.
Ochiai, R. L.
Soofi, S. B.
von Seidlein, Lorenz
Khan, M. J.
Sahito, S. M.
Habib, M. A.
Puri, M. K.
Park, J. K.
You, Y. A.
Ali, M.
Nizami, S. Q.
Acosta, C. J.
Bradley-Sack, R.
Clemens, J. D.
Bhutta, Z. A.
Journal Name Epidemiology and Infection
Publication Date 2012
Volume Number 140
Issue Number 4
ISSN 0950-2688   (check CDU catalogue open catalogue search in new window)
Start Page 665
End Page 672
Total Pages 7
Place of Publication Cambridge, U.K.
Publisher Cambridge University Press
HERDC Category C1 - Journal Article (DIISR)
Abstract We analysed the data from the control group in a typhoid vaccine trial in Karachi to assess the differences in individual-, household- and cluster-level characteristics for developing typhoid fever. The annual incidence of typhoid in children aged 2–16 years in the control arm of the vaccine trial was 151/100 000 population. After adjustment, the risk of typhoid was lower with increasing age [risk ratio (RR) 0·89, 95% confidence interval (CI) 0·83–0·95], was higher with an increase in population density (RR 1·13, 95% CI 1·05–1·21) and was lower in the households using a safe drinking-water source (RR 0·63, 95% CI 0·41–0·99). Typhoid fever affects younger children living in areas of high population density and lack of access to safe water in Pakistan. A combination of environmental and biological interventions is required to prevent the continued epidemiological and economic impact of typhoid fever in high-risk areas of Pakistan.
Keywords Enteric bacteria
epidemiology
infectious disease epidemiology
risk assessment
Salmonella Typhi
DOI http://dx.doi.org/10.1017/S0950268811000938   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)


© copyright

Every reasonable effort has been made to ensure that permission has been obtained for items included in CDU eSpace. If you believe that your rights have been infringed by this repository, please contact digitisation@cdu.edu.au.

 
Versions
Version Filter Type
Access Statistics: 72 Abstract Views, 131 File Downloads  -  Detailed Statistics
Created: Fri, 17 Jan 2014, 01:06:50 CST