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Severe drug-induced hypersensitivity syndrome with a shared HLA-B allele (Case reports)

Harding, Damian J., Subramaniam, Kavitha, MacQuillan, Gerry, Davis, Joshua S. and Nolan, David (2012). Severe drug-induced hypersensitivity syndrome with a shared HLA-B allele (Case reports). Medical Journal of Australia,197(7):411-413.

Document type: Journal Article
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IRMA ID bsmithxPUB133
Title Severe drug-induced hypersensitivity syndrome with a shared HLA-B allele (Case reports)
Author Harding, Damian J.
Subramaniam, Kavitha
MacQuillan, Gerry
Davis, Joshua S.
Nolan, David
Journal Name Medical Journal of Australia
Publication Date 2012
Volume Number 197
Issue Number 7
ISSN 1326-5377   (check CDU catalogue open catalogue search in new window)
Scopus ID 2-s2.0-84871854564
Start Page 411
End Page 413
Total Pages 3
Place of Publication Australia
Publisher Australasian Medical Publishing Company Pty. Ltd.
HERDC Category C2 - Journal Article - Other contributions to refereed journal (internal)
Abstract We describe the first reported cases of phenytoin-related drug-induced hypersensitivity syndrome in unrelated Indigenous Australians with the same HLA-B*56:02 allele. These patients shared common clinical and pathological features, and all three were found to have the otherwise rare HLA-B allele, which might represent a novel genetic susceptibility factor for this syndrome.
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