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Culture and PCR detection of Haemophilus influenzae and Haemophilus haemolyticus in Australian Indigenous children with bronchiectasis

Hare, Kim M., Binks, Michael J., Grimwood, Keith, Chang, Anne B., Leach, Amanda J. and Smith-Vaughan, Heidi C. (2012). Culture and PCR detection of Haemophilus influenzae and Haemophilus haemolyticus in Australian Indigenous children with bronchiectasis. Journal of Clinical Microbiology,50(7):2444-2445.

Document type: Journal Article
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IRMA ID MENbsnellxPUB7
NHMRC Grant No. 545223
Title Culture and PCR detection of Haemophilus influenzae and Haemophilus haemolyticus in Australian Indigenous children with bronchiectasis
Author Hare, Kim M.
Binks, Michael J.
Grimwood, Keith
Chang, Anne B.
Leach, Amanda J.
Smith-Vaughan, Heidi C.
Journal Name Journal of Clinical Microbiology
Publication Date 2012
Volume Number 50
Issue Number 7
ISSN 0095-1137   (check CDU catalogue open catalogue search in new window)
Scopus ID 2-s2.0-84862750027
Start Page 2444
End Page 2445
Total Pages 2
Place of Publication Washington, United States
Publisher American Society for Microbiology
HERDC Category C1 - Journal Article (DIISR)
Abstract A PCR for protein D (hpd#3) was used to differentiate nontypeable Haemophilus influenzae (NTHI) from Haemophilus haemolyticus. While 90% of nasopharyngeal specimens and 100% of lower-airway specimens from 84 Indigenous Australian children with bronchiectasis had phenotypic NTHI isolates confirmed as H. influenzae, only 39% of oropharyngeal specimens with phenotypic NTHI had H. influenzae. The nasopharynx is therefore the preferred site for NTHI colonization studies, and NTHI is confirmed as an important lower-airway pathogen.
DOI http://dx.doi.org/10.1128/JCM.00566-12   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)


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