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Cardiovascular risk assessment in prediabetes and undiagnosed diabetes mellitus study: international collaboration research overview

Nwose, Ezekiel U., Richards, Ross S., Digban, Kester, Bwititi, Philip T., Ennis, Gretchen M., Yee, Kwang Choon, Oguoma, Victor M. and Liberato, Selma C. (2013). Cardiovascular risk assessment in prediabetes and undiagnosed diabetes mellitus study: international collaboration research overview. North American Journal of Medical Sciences,5(11):625-630.

Document type: Journal Article
Citation counts: Scopus Citation Count Cited 0 times in Scopus Article

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IRMA ID 82794376xPUB238
Title Cardiovascular risk assessment in prediabetes and undiagnosed diabetes mellitus study: international collaboration research overview
Author Nwose, Ezekiel U.
Richards, Ross S.
Digban, Kester
Bwititi, Philip T.
Ennis, Gretchen M.
Yee, Kwang Choon
Oguoma, Victor M.
Liberato, Selma C.
Journal Name North American Journal of Medical Sciences
Publication Date 2013
Volume Number 5
Issue Number 11
ISSN 2250-1541   (check CDU catalogue  open catalogue search in new window)
eISSN 1947-2714
Scopus ID 2-s2.0-84888779323
Start Page 625
End Page 630
Total Pages 6
Place of Publication India
Publisher Medknow Publications
HERDC Category C1 - Journal Article (DIISR)
Abstract The study aims to develop a screening protocol for the risk of future cardiovascular disease and diabetes mellitus in people with prediabetes and undiagnosed diabetes; and to establish a framework for early identification and intervention of prediabetes including strategies for holistic management and monitoring of progression. The first phase is to identify prediabetes and undiagnosed diabetes in volunteers who are ≥18-years-old for 5 years. Point-of-care testing and questionnaire will be used to screen for prediabetes and cardiovascular disease. We anticipate screening more than 2000 individuals of both genders by the end of first phase. The second and third phases which shall run for 5-10 years will be longitudinal study involving participants identified in the first phase as having prediabetes without dyslipidaemia, or clinically established cardiovascular disease. The second phase shall focus on preventive management of risk of progress to diabetes with explicit diagnosis of cardiovascular disease. Oxidative stress measurements will be performed cum evaluation of the use of antioxidants, exercise, and nutrition. The third phase will include probing the development of diabetes and cardiovascular disease. Binomial logistic regression would be performed to generate and propose a model chart for the assessment of cardiovascular disease risk in prediabetes.

Keywords Early diagnosis
Early intervention
Holistic health management
Public health screeing
DOI http://dx.doi.org/10.4103/1947-2714.122303   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)


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