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Surprisingly low seroprevalence for Burkholderia pseudomallei in exposed healthy adults in the Darwin region of tropical Australia where melioidosis is highly endemic

James, Gemma L., Delaney, Ben, Ward, Linda M., Freeman, Kevin, Mayo, Mark J. and Currie, Bart J. (2013). Surprisingly low seroprevalence for Burkholderia pseudomallei in exposed healthy adults in the Darwin region of tropical Australia where melioidosis is highly endemic. Clinical and Vaccine Immunology,20(5):759-760.

Document type: Journal Article
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IRMA ID bsmithxPUB165
NHMRC Grant No. 605820
Title Surprisingly low seroprevalence for Burkholderia pseudomallei in exposed healthy adults in the Darwin region of tropical Australia where melioidosis is highly endemic
Author James, Gemma L.
Delaney, Ben
Ward, Linda M.
Freeman, Kevin
Mayo, Mark J.
Currie, Bart J.
Journal Name Clinical and Vaccine Immunology
Publication Date 2013
Volume Number 20
Issue Number 5
ISSN 1556-6811   (check CDU catalogue  open catalogue search in new window)
Scopus ID 2-s2.0-84876883277
Start Page 759
End Page 760
Total Pages 2
Place of Publication United States
Publisher American Society for Microbiology
HERDC Category C1 - Journal Article (DIISR)
Abstract In the Darwin region of Australia where melioidosis is highly endemic, only 11/354 (3%) healthy residents were seropositive by indirect hemagglutination assay, despite extensive exposure to Burkholderia pseudomallei. None developed melioidosis, but some described a prior self-limiting illness. This seropositivity rate is much lower than that seen in northeast Thailand, where melioidosis is similarly highly endemic, potentially reflecting important differences between these two locations in the epidemiology of melioidosis.

DOI http://dx.doi.org/10.1128/CVI.00021-13   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)
Additional Notes Copyright © 2013, American Society for Microbiology. All Rights Reserved


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