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Mothers After Gestational Diabetes in Australia Diabetes Prevention Program (MAGDA-DPP) post-natal intervention: study protocol for a randomized controlled trial

Shih, Sophy T. F., Davis-Lameloise, Nathalie, Janus, Edward D., Wildey, Carol, Versace, Vincent L., Hagger, Virginia, Asproloupos, Dino, O'Reilly, Sharleen, Phillips, Paddy A., Ackland, Michael, Skinner, Timothy C., Oats, Jeremy, Carter, Rob, Best, James D. and Dunbar, James A. (2013). Mothers After Gestational Diabetes in Australia Diabetes Prevention Program (MAGDA-DPP) post-natal intervention: study protocol for a randomized controlled trial. Trials,14(1):339-1-339-10.

Document type: Journal Article
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Title Mothers After Gestational Diabetes in Australia Diabetes Prevention Program (MAGDA-DPP) post-natal intervention: study protocol for a randomized controlled trial
Author Shih, Sophy T. F.
Davis-Lameloise, Nathalie
Janus, Edward D.
Wildey, Carol
Versace, Vincent L.
Hagger, Virginia
Asproloupos, Dino
O'Reilly, Sharleen
Phillips, Paddy A.
Ackland, Michael
Skinner, Timothy C.
Oats, Jeremy
Carter, Rob
Best, James D.
Dunbar, James A.
Journal Name Trials
Publication Date 2013
Volume Number 14
Issue Number 1
ISSN 1745-6215   (check CDU catalogue open catalogue search in new window)
Scopus ID 2-s2.0-84885526809
Start Page 339-1
End Page 339-10
Total Pages 10
Place of Publication United Kingdom
Publisher BioMed Central Ltd.
HERDC Category C2 - Journal Article - Other contributions to refereed journal (internal)
Abstract Background
Gestational diabetes mellitus (GDM) is defined as glucose intolerance with its onset or first recognition during pregnancy. Post-GDM women have a life-time risk exceeding 70% of developing type 2 diabetes mellitus (T2DM). Lifestyle modifications reduce the incidence of T2DM by up to 58% for high-risk individuals.

Methods/Design
The Mothers After Gestational Diabetes in Australia Diabetes Prevention Program (MAGDA-DPP) is a randomized controlled trial aiming to assess the effectiveness of a structured diabetes prevention intervention for post-GDM women. This trial has an intervention group participating in a diabetes prevention program (DPP), and a control group receiving usual care from their general practitioners during the same time period. The 12-month intervention comprises an individual session followed by five group sessions at two-week intervals, and two follow-up telephone calls. A total of 574 women will be recruited, with 287 in each arm. The women will undergo blood tests, anthropometric measurements, and self-reported health status, diet, physical activity, quality of life, depression, risk perception and healthcare service usage, at baseline and 12 months. At completion, primary outcome (changes in diabetes risk) and secondary outcome (changes in psychosocial and quality of life measurements and in cardiovascular disease risk factors) will be assessed in both groups.

Discussion
This study aims to show whether MAGDA-DPP leads to a reduction in diabetes risk for post-GDM women. The characteristics that predict intervention completion and improvement in clinical and behavioral measures will be useful for further development of DPPs for this population.


Keywords Gestational diabetes
Post-natal
Lifestyle intervention
Type 2 diabetes prevention
DOI http://dx.doi.org/10.1186/1745-6215-14-339   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)
Additional Notes This is an Open Access article distributed under the terms of the Creative Commons Attribution License 2.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Description for Link Link to CC Attribution 2.0 License
URL https://creativecommons.org/licenses/by/2.0/au/legalcode


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