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Pregnancy And Neonatal Diabetes Outcomes in Remote Australia (PANDORA) Study

Maple-Brown, Louise J., Brown, Alex, Lee, I-Lynn, Connors, Christine M., Oats, Jeremy, McIntyre, Harold, Whitbread, Cherie, Moore, Elizabeth, Longmore, Danielle, Dent, Glynis, Corpus, Sumaria, Kirkwood, Marie T., Svenson, Stacey A., van Dokkum, Paula, Chitturi, Sridhar, Dempsey, Karen, Dowden, Michelle C., Boyle, Jacqueline A., Sayers, Susan, O'Dea, Kerin and et al. (2013). Pregnancy And Neonatal Diabetes Outcomes in Remote Australia (PANDORA) Study. BMC Pregnancy and Childbirth,13:221-1-221-8.

Document type: Journal Article
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IRMA ID cmartelxPUB147
NHMRC Grant No. 1032116
605837
Title Pregnancy And Neonatal Diabetes Outcomes in Remote Australia (PANDORA) Study
Author Maple-Brown, Louise J.
Brown, Alex
Lee, I-Lynn
Connors, Christine M.
Oats, Jeremy
McIntyre, Harold
Whitbread, Cherie
Moore, Elizabeth
Longmore, Danielle
Dent, Glynis
Corpus, Sumaria
Kirkwood, Marie T.
Svenson, Stacey A.
van Dokkum, Paula
Chitturi, Sridhar
Dempsey, Karen
Dowden, Michelle C.
Boyle, Jacqueline A.
Sayers, Susan
O'Dea, Kerin
et al.
Journal Name BMC Pregnancy and Childbirth
Publication Date 2013
Volume Number 13
ISSN 1471-2393   (check CDU catalogue open catalogue search in new window)
Scopus ID 2-s2.0-84888308824
Start Page 221-1
End Page 221-8
Total Pages 1
Place of Publication United Kingdom
Publisher BioMed Central Ltd.
HERDC Category C2 - Journal Article - Other contributions to refereed journal (internal)
Abstract Background
Diabetes in pregnancy carries an increased risk of adverse pregnancy outcomes for both the mother and foetus, but it also provides an excellent early opportunity for intervention in the life course for both mother and baby. In the context of the escalating epidemic of chronic diseases among Indigenous Australians, it is vital that this risk is reduced as early as possible in the life course of the individual. The aims of the PANDORA Study are to: (i) accurately assess rates of diabetes in pregnancy in the Northern Territory (NT) of Australia, where 38% of babies are born to Indigenous mothers; (ii) assess demographic, clinical, biochemical, anthropometric, socioeconomic and early life development factors that may contribute to key maternal and neonatal birth outcomes associated with diabetes in pregnancy; and (iii) monitor relevant post-partum clinical outcomes for both the mothers and their babies.

Methods/Design
Eligible participants are all NT women with diabetes in pregnancy aged 16 years and over. Information collected includes: standard antenatal clinical information, diagnosis and management of diabetes in pregnancy, socio-economic status, standard clinical birth information (delivery, gestational age, birth weight, adverse antenatal and birth outcomes). Cord blood is collected at the time of delivery and detailed neonatal anthropometric measurements performed within 72 hours of birth. Information will also be collected regarding maternal post-partum glucose tolerance and cardio-metabolic risk factor status, breastfeeding and growth of the baby up to 2 years post-partum in the first instance.

Discussion
This study will accurately document rates and outcomes of diabetes in pregnancy in the NT of Australia, including the high-risk Indigenous Australian population. The results of this study should contribute to policy and clinical guidelines with the goal of reducing the future risk of obesity and diabetes in both mothers and their offspring.
Keywords Diabetes in pregnancey
Gestational diabetes
Antenatal care
Birth weight
Noenatal body composition
Anthropometry
Indigenous Australian
Aboriginal
DOI http://dx.doi.org/10.1186/1471-2393-13-221   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)
Additional Notes This is an Open Access article distributed under the terms of the Creative Commons Attribution License 3.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Description for Link Link to CC Attribution 3.0 License
URL https://creativecommons.org/licenses/by/3.0/au/legalcode


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