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Inducible nitric oxide synthase (NOS2) promoter CCTTT repeat polymorphism: relationship to in vivo nitric oxide production/NOS activity in an asymptomatic malaria-endemic population

Boutlis, Craig, Hobbs, M. R., Marsh, RL, Misukonis, M. A., Tkachuk, A. N., Lagog, M., Booth, J., Granger, D. L., Bockarie, M. J., Mgone, C. S., Levesque, M. C., Weinberg, J. B. and Anstey, Nicholas M. (2003). Inducible nitric oxide synthase (NOS2) promoter CCTTT repeat polymorphism: relationship to in vivo nitric oxide production/NOS activity in an asymptomatic malaria-endemic population. American Journal of Tropical Medicine and Hygiene,69(6):569-573.

Document type: Journal Article
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Title Inducible nitric oxide synthase (NOS2) promoter CCTTT repeat polymorphism: relationship to in vivo nitric oxide production/NOS activity in an asymptomatic malaria-endemic population
Author Boutlis, Craig
Hobbs, M. R.
Marsh, RL
Misukonis, M. A.
Tkachuk, A. N.
Lagog, M.
Booth, J.
Granger, D. L.
Bockarie, M. J.
Mgone, C. S.
Levesque, M. C.
Weinberg, J. B.
Anstey, Nicholas M.
Journal Name American Journal of Tropical Medicine and Hygiene
Publication Date 2003
Volume Number 69
Issue Number 6
ISSN 1476-1645   (check CDU catalogue  open catalogue search in new window)
Start Page 569
End Page 573
Total Pages 5
Publisher The American Society of Tropical Medicine and Hygiene
Language English
Field of Research 1117 - Public Health and Health Services
HERDC Category C1 - Journal Article (DEST)
Abstract Polymorphisms in the inducible nitric oxide synthase gene (NOS2) promoter have been associated with clinical outcome from malaria. These include a CCTTT repeat (CCTTTn) 2.5 kilobases upstream from the NOS2 transcription start site, and two single nucleotide substitutions: G--
Keywords Australia
nitric oxide
Papua New Guinea
Polymorphism,Genetic
Additional Notes 3989 (Journal) DA - 20040126IS - 0002-9637 (Print)LA - engPT - Journal ArticlePT - Research Support, Non-U.S. Gov'tPT - Research Support, U.S. Gov't, Non-P.H.SPT - Research Support, U.S. Gov't, P.H.SRN - 10102-43-9 (Nitric Oxide)RN - EC 1.14.13.39 (NOS2A protein, human)RN - EC 1.14.13.39 (Nitric Oxide Synthase)RN - EC 1.14.13.39 (Nitric Oxide Synthase Type II)SB - AIMSB - IM
Description for Link Link to Abstract
URL http://www.ajtmh.org/cgi/content/abstract/69/6/569
 
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