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Non-CF bronchiectasis: Clinical and HRCT evaluation

Chang, Anne B., Masel, J. P., Boyce, N. C., Wheaton, G. and Torzillo, Paul J. (2003). Non-CF bronchiectasis: Clinical and HRCT evaluation. Pediatric Pulmonology,35(6):477-483.

Document type: Journal Article
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Title Non-CF bronchiectasis: Clinical and HRCT evaluation
Author Chang, Anne B.
Masel, J. P.
Boyce, N. C.
Wheaton, G.
Torzillo, Paul J.
Journal Name Pediatric Pulmonology
Publication Date 2003
Volume Number 35
Issue Number 6
ISSN 8755-6863   (check CDU catalogue open catalogue search in new window)
Start Page 477
End Page 483
Total Pages 7
Place of Publication US
Publisher John Wiley & Sons, Inc.
Language English
Field of Research 1114 - Paediatrics and Reproductive Medicine
HERDC Category C1 - Journal Article (DEST)
Abstract Childhood bronchiectasis not related to underlying disease is still common in some populations in affluent countries. The aims of the study were to: 1) describe demographics, 2) evaluate the effectiveness of routine investigations, and 3) determine the relationship between spirometry and radiology scoring systems, in children with chronic suppurative lung disease (CSLD) living in Central Australia. Data of children living in Central Australia aged >/=15 years with noncystic fibrosis CSLD were identified over 2 years. Chest high-resolution computed tomography (HRCT) scans were interpreted by a pediatric radiologist and scored according to three systems. Sixty-five children were identified, resulting in a prevalence of at least 14.7/1,000 aboriginal children aged >/=15 years. Comorbidities (most common: suppurative otitis media in <70%) and early hospitalisation for pneumonia were common (median age, 0.5 years). Previous admissions for pneumonia were almost universally present and significantly more common than bronchiolitis (95% CI for proportional difference, 0.4-0.51). Although the majority did not have a treatable underlying cause, investigations had significant impact on management in 12.3% of children. None of the chest HRCT scores related to any spirometry data. In conclusion, CSLD is unacceptably common in indigenous children of this region, commences early in life, and is associated with significant comorbidities. Spirometry data do not reflect the severity of lung disease in HRCT scans. While improvement in the living standards is of utmost importance, the medical management that includes thorough investigations of these children should not be neglected.
Keywords bronchiectasis
chronic lung disease
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Created: Mon, 17 Dec 2007, 09:02:11 CST