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Strains of Streptococcus pyogenes from severe invasive infections bind HEp2 and HaCaT cells more avidly than strains from uncomplicated infections

Edwards, Mandy L., Fagan, Peter K., Smith-Vaughan, Heidi C., Currie, Bart J. and Sriprakash, Kadaba S. (2003). Strains of Streptococcus pyogenes from severe invasive infections bind HEp2 and HaCaT cells more avidly than strains from uncomplicated infections. Journal of Clinical Microbiology,41(8):3936-3938.

Document type: Journal Article
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Title Strains of Streptococcus pyogenes from severe invasive infections bind HEp2 and HaCaT cells more avidly than strains from uncomplicated infections
Author Edwards, Mandy L.
Fagan, Peter K.
Smith-Vaughan, Heidi C.
Currie, Bart J.
Sriprakash, Kadaba S.
Journal Name Journal of Clinical Microbiology
Publication Date 2003
Volume Number 41
Issue Number 8
ISSN 1098-660X   (check CDU catalogue open catalogue search in new window)
Start Page 3936
End Page 3938
Total Pages 3
Place of Publication Washington, United States
Publisher American Society for Microbiology
Language English
Field of Research 0605 - Microbiology
0707 - Veterinary Sciences
1108 - Medical Microbiology
HERDC Category C1 - Journal Article (DEST)
Abstract Epidemiologically unrelated Streptococcus pyogenes strains isolated from blood, throat, and skin were assayed for adherence to HEp2 and HaCaT cells. Invasive isolates showed significantly higher avidity for these cell lines than isolates from skin and throat. In general, S. pyogenes showed greater binding to HaCaT cells than to HEp2 cells.
Keywords cells
infections
Streptococcus pyogenes
DOI http://dx.doi.org/10.1128/JCM.41.8.3936-3938.2003   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)
Additional Notes Copyright by the American Society of Microbiology


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