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What Drives the Occurrence of the Melioidosis Bacterium Burkholderia pseudomallei in Domestic Gardens?

Kaestli, Mirjam E., Harrington, Glenda I., Mayo, Mark J., Chatfield, Mark D., Harrington, Ian B., Hill, Audrey A., Munksgaard, Niels C., Gibb, Karen S. and Currie, Bart J. (2015). What Drives the Occurrence of the Melioidosis Bacterium Burkholderia pseudomallei in Domestic Gardens?<br />. PLoS Neglected Tropical Diseases,9(3 - Article No. e0003635):1-16.

Document type: Journal Article
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ARC Grant No. LP110100691
IRMA ID 11381xPUB62
NHMRC Grant No. 1046812
Title What Drives the Occurrence of the Melioidosis Bacterium Burkholderia pseudomallei in Domestic Gardens?
Author Kaestli, Mirjam E.
Harrington, Glenda I.
Mayo, Mark J.
Chatfield, Mark D.
Harrington, Ian B.
Hill, Audrey A.
Munksgaard, Niels C.
Gibb, Karen S.
Currie, Bart J.
Journal Name PLoS Neglected Tropical Diseases
Publication Date 2015
Volume Number 9
Issue Number 3 - Article No. e0003635
ISSN 1935-2727   (check CDU catalogue open catalogue search in new window)
eISSN 1935-2735
Scopus ID 2-s2.0-84928776951
Start Page 1
End Page 16
Total Pages 16
Place of Publication United States
Publisher Public Library of Science
HERDC Category C1 - Journal Article (DIISR)
Abstract Melioidosis is an often fatal infectious disease affecting humans and animals in tropical regions and is caused by the saprophytic environmental bacterium Burkholderia pseudomallei. Domestic gardens are not only a common source of exposure to soil and thus to B. pseudomallei, but they also have been found to contain more B. pseudomallei than other environments. In this study we addressed whether anthropogenic manipulations common to gardens such as irrigation or fertilizers change the occurrence of B. pseudomallei. We conducted a soil microcosm experiment with a range of fertilizers and soil types as well as a longitudinal interventional study over three years on an experimental fertilized field site in an area naturally positive for B. pseudomallei. Irrigation was the only consistent treatment to increase B. pseudomallei occurrence over time. The effects of fertilizers upon these bacteria depended on soil texture, physicochemical soil properties and biotic factors. Nitrates and urea increased B. pseudomallei load in sand while phosphates had a positive effect in clay. The high buffering and cation exchange capacities of organic material found in a commercial potting mix led to a marked increase in soil salinity with no survival of B. pseudomallei after four weeks in the potting mix sampled. Imported grasses were also associated with B. pseudomallei occurrence in a multivariate model. With increasing population density in endemic areas these findings inform the identification of areas in the anthropogenic environment with increased risk of exposure to B. pseudomallei.
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Additional Notes This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Description for Link Link to CC Attribution 4.0 License

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