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Perspectives on infective ear disease (otitis media) in Indigenous Australian children

Leach, Amanda J. and Morris, Peter S. (2001). Perspectives on infective ear disease (otitis media) in Indigenous Australian children. Journal of Paediatrics and Child Health,37(6):529-530.

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Title Perspectives on infective ear disease (otitis media) in Indigenous Australian children
Author Leach, Amanda J.
Morris, Peter S.
Journal Name Journal of Paediatrics and Child Health
Publication Date 2001
Volume Number 37
Issue Number 6
ISSN 1440-1754   (check CDU catalogue open catalogue search in new window)
Start Page 529
End Page 530
Total Pages 2
Place of Publication UK
Publisher Wiley-Blackwell Publishing Ltd.
Language English
Field of Research 320000 Medical and Health Sciences
Abstract Australian Aboriginal children experience the highest rates of bacterial respiratory diseases reported in the literature. Neonatal acquisition of multiple bacterial pathogenic species and strains predicts persistent and severe disease throughout childhood, particularly infective ear disease. The dynamics of bacterial nasopharyngeal colonization and transmission are poorly understood. The importance of host factors, bacterial competition and co-operation in the transition from asymptomatic carriage to disease are also uncertain. Treatment outcomes are poor, possibly due to the high density of bacterial infection following early age exposure, poor compliance and increasing levels of antibiotic resistance. The relationship between antibiotic use, clinical outcomes and bacterial resistance needs to be better understood in high-risk populations if the benefits associated with treatment are to be maximized. While there is an urgent need for vaccines, the early age of infection and the high rates of transmission and bacterial antigenic diversity mean these may also be less effective than predicted from studies in low-risk populations.
Keywords Australian
Ear disease
otitis media
DOI   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)
Additional Notes 1653 (Journal)
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Created: Mon, 17 Dec 2007, 09:02:11 CST