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Control of endemic MRSA — what is the evidence? A personal view

Marshall,C, Wesselingh, S, McDonald, M and Spelman, D (2004). Control of endemic MRSA — what is the evidence? A personal view. The Journal of Hospital Infection,56(4):253-268.

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Title Control of endemic MRSA — what is the evidence? A personal view
Author Marshall,C
Wesselingh, S
McDonald, M
Spelman, D
Journal Name The Journal of Hospital Infection
Publication Date 2004
Volume Number 56
Issue Number 4
ISSN 1532-2939   (check CDU catalogue open catalogue search in new window)
Start Page 253
End Page 268
Total Pages 16
Place of Publication Kent, UK
Publisher W.B. Saunders Co. Ltd.
HERDC Category C1 - Journal Article (DEST)
Abstract Although there is extensive literature on the control of MRSA, when that concerning epidemics is excluded, only a limited amount remains regarding the control of endemic MRSA. Several guidelines have been recently published recommending stringent control measures, which are often suggested based on their success in controlling MRSA outbreaks in hospitals with few MRSA or in containing MRSA cases introduced into a hospital with no MRSA. In these settings, multiple measures are usually introduced with apparently successful results. However, results may not be generalizable to other settings and we do not know the minimum effective measures required for MRSA containment. This paper aims critically to review the literature to determine whether evidence exists for the value of the infection control measures that are widely recommended in the endemic setting. Much of this literature is based on observational studies, with few randomized, controlled trials having been conducted. More well-designed studies are required before many of the principles on which we build infection control programmes can be regarded as evidence based.
Keywords endemic
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Created: Mon, 17 Dec 2007, 09:02:11 CST