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Albuminuria in Aboriginal children: An evolution over a continuum into adult life

Singh, GR and Hoy, WE (2006). Albuminuria in Aboriginal children: An evolution over a continuum into adult life. In: Australia and New Zealand Society of Nephrology Annual Scientific Conference, Melbourne Exhibition and Convention Centre, Melbourne, 14 - 19 August, 2006.

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Author Singh, GR
Hoy, WE
Title Albuminuria in Aboriginal children: An evolution over a continuum into adult life
Conference Name Australia and New Zealand Society of Nephrology Annual Scientific Conference
Conference Location Melbourne Exhibition and Convention Centre, Melbourne
Conference Dates 14 - 19 August, 2006
Conference Publication Title Proceedings of the Australia and New Zealand Society of Nephrology Annual Scientific Conference
Publication Year 2006
HERDC Category C1 - Journal Article (DEST)
Abstract Purpose: Albuminuria marks the renal disease underlying the high rates of renal failure in Australian Aborigines. Rates of albuminuria are high even in the youngest adults, and increase with further ageing. Patterns in Aboriginal children, have, however, been less well defined. We described urinary albumin excretion in Aboriginal children and its relationships to patterns in adults in one high risk remote Aboriginal community. Methods: A cross sectional screen of people (n=1452: age range 5-78 year) with >85% participation, which included the urine albumin:creatinine ratio (ACR). Results: The table shows means, geometric means and rates of categories of elevated ACR with age. Discussion: Albuminuria gradually increases with age from early childhood, both in proportion of people affected and in severity. This argues against the sudden impact of a one-off risk factor or event in precipitating renal disease and fits the hypothesis of a predisposition (set by low birth weight, poor infant circumstances etc) and compounded by multiple adverse factors (infections, obesity etc) over the life course of an individual.
Keyword Aboriginal
Adult
Albuminuria
children
Additional Notes 4139 (Generic Abstract)
 
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Created: Mon, 17 Dec 2007, 09:02:11 CST