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Carriage of multiple ribotypes of non-encapsulated Haemophilus influenzae in Aboriginal infants with otitis media

Smith-Vaughan, Heidi C., Leach, Amanda J., Shelby-James, T. B., Kemp, K., Kemp, David J. and Mathews, John D. (1996). Carriage of multiple ribotypes of non-encapsulated Haemophilus influenzae in Aboriginal infants with otitis media. Epidemiology and infection,116(2):177-183.

Document type: Journal Article
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Title Carriage of multiple ribotypes of non-encapsulated Haemophilus influenzae in Aboriginal infants with otitis media
Author Smith-Vaughan, Heidi C.
Leach, Amanda J.
Shelby-James, T. B.
Kemp, K.
Kemp, David J.
Mathews, John D.
Journal Name Epidemiology and infection
Publication Date 1996
Volume Number 116
Issue Number 2
ISSN 0950-2688   (check CDU catalogue  open catalogue search in new window)
Start Page 177
End Page 183
Total Pages 7
Place of Publication Cambridge, UK
Publisher Cambridge University Press
HERDC Category C1 - Journal Article (DEST)
Abstract Ribotyping with the restriction enzyme XbaI was used to study the dynamics of carriage of non-encapsulated Haemophilus influenzae (NCHi) in Aboriginal infants at risk of otitis media. Carriage rates of NCHi in the infants in the community were very high ; the median age for detection was 50 days and colonization was virtually 100% by 120 days of age and persisted at a high level throughout the first year of life [1]. Eighteen different ribotypes of NCHi were identified from 34 positive swabs taken from 3 infants over a period of 9 months. The same ribotypes were recovered for up to 3 months from consecutive swabs of individual infants, and 12 of 27 swabs (44.4 %) yielded two ribotypes from four colonies typed. Statistical analysis suggested that most swabs would have been positive for two ribotypes if enough colonies had been typed although the second most frequent ribotype was detected on average in only 13 % of strains. Early colonization and carriage of multiple ribotypes of NCHi may help to explain the chronicity of carriage and thus the persistence of otitis media in Aboriginal infants.
Keywords Aboriginal
Haemophilus influenzae
Infant
otitis media
ribotypes
DOI http://dx.doi.org/10.1017/S0950268800052419   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)
Additional Notes 4381 (Journal)
 
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