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Absence of an Important Vaccine and Diagnostic Target in Carriage- and Disease-Related Nontypeable Haemophilus influenzae

Smith-Vaughan, Heidi C., Chang, Anne B., Sarovich, Derek, Marsh, Robyn L., Grimwood, Keith, Leach, Amanda J., Morris, Peter S. and Price, Erin P. (2014). Absence of an Important Vaccine and Diagnostic Target in Carriage- and Disease-Related Nontypeable Haemophilus influenzae. Clinical and Vaccine Immunology,21(2):250-252.

Document type: Journal Article
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IRMA ID cmartelxPUB136
Title Absence of an Important Vaccine and Diagnostic Target in Carriage- and Disease-Related Nontypeable Haemophilus influenzae
Author Smith-Vaughan, Heidi C.
Chang, Anne B.
Sarovich, Derek
Marsh, Robyn L.
Grimwood, Keith
Leach, Amanda J.
Morris, Peter S.
Price, Erin P.
Journal Name Clinical and Vaccine Immunology
Publication Date 2014
Volume Number 21
Issue Number 2
ISSN 1556-6811   (check CDU catalogue  open catalogue search in new window)
Scopus ID 2-s2.0-84893307727
Start Page 250
End Page 252
Total Pages 3
Place of Publication United States of America
Publisher American Society for Microbiology
HERDC Category C1 - Journal Article (DIISR)
Abstract Nontypeable Haemophilus influenzae (NTHi)-associated disease is a major health problem globally. Whole-genome sequence analysis identified the absence of hpd genes encoding Haemophilus protein D in 3 of 16 phylogenetically distinct NTHi isolates. This novel finding is of potential clinical significance, as protein D and hpd represent important NTHi vaccine antigen and diagnostic targets, respectively.

DOI http://dx.doi.org/10.1128/CVI.00632-13   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)
 
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