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Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: updated recommendations from the World Health Organization Pneumococcal Carriage Working Group

Satzke, Catherine, Turner, Paul, Virolainen-Julkunen, Anni, Adrian, Peter, Antonio, Martin, Hare, Kim M., Henao-Restrepo, Ana, Leach, Amanda J., Klugman, Keith, Porter, Barbara, Sa-Leao, Raquel, Scott, J., Nohynek, Hanna and O'Brien, Katherine (2014). Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: updated recommendations from the World Health Organization Pneumococcal Carriage Working Group. Vaccine,32(1):165-179.

Document type: Journal Article
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IRMA ID cmartelxPUB156
Title Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: updated recommendations from the World Health Organization Pneumococcal Carriage Working Group
Author Satzke, Catherine
Turner, Paul
Virolainen-Julkunen, Anni
Adrian, Peter
Antonio, Martin
Hare, Kim M.
Henao-Restrepo, Ana
Leach, Amanda J.
Klugman, Keith
Porter, Barbara
Sa-Leao, Raquel
Scott, J.
Nohynek, Hanna
O'Brien, Katherine
Journal Name Vaccine
Publication Date 2014
Volume Number 32
Issue Number 1
ISSN 0264-410X   (check CDU catalogue open catalogue search in new window)
Scopus ID 2-s2.0-84891951124
Start Page 165
End Page 179
Total Pages 15
Place of Publication United Kingdom
Publisher Elsevier Ltd
HERDC Category C1 - Journal Article (DIISR)
Abstract In 2003 the World Health Organization (WHO) convened a working group and published a set of standard methods for studies measuring nasopharyngeal carriage of Streptococcus pneumoniae (the pneumococcus). The working group recently reconvened under the auspices of the WHO and updated the consensus standard methods. These methods describe the collection, transport and storage of nasopharyngeal samples, as well as provide recommendations for the identification and serotyping of pneumococci using culture and non-culture based approaches. We outline the consensus position of the working group, the evidence supporting this position, areas worthy of future research, and the epidemiological role of carriage studies. Adherence to these methods will reduce variability in the conduct of pneumococcal carriage studies undertaken in the context of pneumococcal vaccine trials, implementation studies, and epidemiology studies more generally so variability in methodology does not confound the interpretation of study findings.
Keywords Nasopharynx
Carriage
Colonization
Pneumococcus
DOI http://dx.doi.org/10.1016/j.vaccine.2013.08.062   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)
 
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