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Implementation of POCT in the diabetic clinic in a large hospital

Tanyanyiwa, D., Dandara, C., Bhana, S.A., Pauly, B., Marule, F., Ramokoka, M., Bwititi, P., Nwose, Ezekiel and Nkosi, B. (2015). Implementation of POCT in the diabetic clinic in a large hospital. African Health Sciences,15(3):902-907.

Document type: Journal Article
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IRMA ID 81144320xPUB105
Title Implementation of POCT in the diabetic clinic in a large hospital
Author Tanyanyiwa, D.
Dandara, C.
Bhana, S.A.
Pauly, B.
Marule, F.
Ramokoka, M.
Bwititi, P.
Nwose, Ezekiel
Nkosi, B.
Journal Name African Health Sciences
Publication Date 2015
Volume Number 15
Issue Number 3
ISSN 1680-6905   (check CDU catalogue  open catalogue search in new window)
Scopus ID 2-s2.0-84941351751
Start Page 902
End Page 907
Total Pages 6
Place of Publication Uganda
Publisher Markerere University * Medical School
HERDC Category C1 - Journal Article (DIISR)
Abstract Aim:
Point-of-care testing (POCT) is gaining renewed interest, especially in resource-limiting primary health care, due to rise in prevalence of communicable and non-communicable diseases hence POCT needscontinuous appraisal.

Methods:
Random glucose and glycated haemoglobin (HbA1c) were measured in 104 diabetic patients using standard laboratory multichannel analyzer 917. The utility of venous blood compared to capillary blood in measuring HbA1c was evaluated in a subset of 20 patients using a POCT device, DCA Vantage. Lastly, the POCT was validated against the laboratory multichannel analyser 917, in measurement of HbA1c in a second subset of 46 patients.

Results:
Random blood glucose levels and HbA1c levels moderately correlated (r2 = 0.56; p < 0.0001). Random glucose tests showed that 41% of the patients had poor glycaemic control while HbA1c showed 74%. Venous and capillary blood in HbA1c showed strong correlation (r2 = 0.89440; p < 0.001. There was also strong correlation (r = 0.9802; p < 0.0001) in HbA1c measured using the DCA Vantage and the standard laboratory analyser, Multichannel Analyser 917.

Conclusion:
Venous or capillary blood can be used in POCT for HbA1c. POCT is ideal for monitoring glucose control and management of diabetes in resource-limited countries such as South Africa
Keywords POCT - Post-of-care testing
POST - Point-of-service testing
Diabetes mellitus
DOI http://dx.doi.org/10.4314/ahs.v15i3.26   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)
 
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