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High burden of RSV hospitalization in very young children: a data linkage study

Homaira, Nusrat, Oei, Ju Lee, Mallitt, Kylie-Ann, Abdel-Latif, M. E., Hilder, L., Bajuk, B., Lui, K., Ferson, M., Nurkic, A., Chambers, G. M., Rawlinson, W., Snelling, Thomas L. and Jaffe, A. (2015). High burden of RSV hospitalization in very young children: a data linkage study. Epidemiology and Infection,144(8):1612-1621.

Document type: Journal Article
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IRMA ID 81144320xPUB169
Title High burden of RSV hospitalization in very young children: a data linkage study
Author Homaira, Nusrat
Oei, Ju Lee
Mallitt, Kylie-Ann
Abdel-Latif, M. E.
Hilder, L.
Bajuk, B.
Lui, K.
Ferson, M.
Nurkic, A.
Chambers, G. M.
Rawlinson, W.
Snelling, Thomas L.
Jaffe, A.
Journal Name Epidemiology and Infection
Publication Date 2015
Volume Number 144
Issue Number 8
ISSN 0950-2688   (check CDU catalogue open catalogue search in new window)
Scopus ID 2-s2.0-84949558803
Start Page 1612
End Page 1621
Total Pages 10
Place of Publication United Kingdom
Publisher Cambridge University Press
HERDC Category C1 - Journal Article (DIISR)
Abstract Linked administrative population data were used to estimate the burden of childhood respiratory syncytial virus (RSV) hospitalization in an Australian cohort aged <5 years. RSV-coded hospitalizations data were extracted for all children aged <5 years born in New South Wales (NSW), Australia between 2001 and 2010. Incidence was calculated as the total number of new episodes of RSV hospitalization divided by the child-years at risk. Mean cost per episode of RSV hospitalization was estimated using public hospital cost weights. The cohort comprised of 870 314 children. The population-based incidence/1000 child-years of RSV hospitalization for children aged <5 years was 4·9 with a rate of 25·6 in children aged <3 months. The incidence of RSV hospitalization (per 1000 child-years) was 11·0 for Indigenous children, 81·5 for children with bronchopulmonary dysplasia (BPD), 10·2 for preterm children with gestational age (GA) 32–36 weeks, 27·0 for children with GA 28–31 weeks, 39·0 for children with GA <28 weeks and 6·7 for term children with low birthweight. RSV hospitalization was associated with an average annual cost of more than AUD 9 million in NSW. RSV was associated with a substantial burden of childhood hospitalization specifically in children aged <3 months and in Indigenous children and children born preterm or with BPD.
Keywords Epidemiology
estimating disease prevalence
global vaccine issues
infectious disease epidemiology
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