Charles Darwin University

CDU eSpace
Institutional Repository

 
CDU Staff and Student only
 

Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management

Tong, Steven Y. C., Davis, Joshua S., Eichenberger, Emily, Holland, Thomas L. and Fowler, Vance G., Jr. (2015). Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management. Clinical Microbiology Reviews,28(3):603-661.

Document type: Journal Article
Citation counts: Altmetric Score Altmetric Score is 54
Google Scholar Search Google Scholar

IRMA ID 11381xPUB99
Title Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management
Author Tong, Steven Y. C.
Davis, Joshua S.
Eichenberger, Emily
Holland, Thomas L.
Fowler, Vance G., Jr.
Journal Name Clinical Microbiology Reviews
Publication Date 2015
Volume Number 28
Issue Number 3
ISSN 0893-8512   (check CDU catalogue  open catalogue search in new window)
Start Page 603
End Page 661
Total Pages 59
Place of Publication United States of America
Publisher American Society for Microbiology
HERDC Category C1 - Journal Article (DIISR)
Abstract Staphylococcus aureus is a major human pathogen that causes a wide range of clinical infections. It is a leading cause of bacteremia and infective endocarditis as well as osteoarticular, skin and soft tissue, pleuropulmonary, and device-related infections. This review comprehensively covers the epidemiology, pathophysiology, clinical manifestations, and management of each of these clinical entities. The past 2 decades have witnessed two clear shifts in the epidemiology of S. aureus infections: first, a growing number of health care-associated infections, particularly seen in infective endocarditis and prosthetic device infections, and second, an epidemic of community-associated skin and soft tissue infections driven by strains with certain virulence factors and resistance to β-lactam antibiotics. In reviewing the literature to support management strategies for these clinical manifestations, we also highlight the paucity of high-quality evidence for many key clinical questions.
DOI http://dx.doi.org/10.1128/CMR.00134-14   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)
 
Versions
Version Filter Type
Access Statistics: 23 Abstract Views  -  Detailed Statistics
Created: Tue, 26 Jul 2016, 12:48:30 CST