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Northern Territory Perspectives on Heart Failure with Comorbidities - Understanding Trial Validity and Exploring Collaborative Opportunities to Broaden the Evidence Base

Iyngkaran, P., Majoni, William, Cass, Alan, Sanders, Prashanthan, Ronco, C., Brady, Stephen, Kangaharan, N., Ilton, Marcus, Hare, D. L. and Thomas, Merlin C. (2015). Northern Territory Perspectives on Heart Failure with Comorbidities - Understanding Trial Validity and Exploring Collaborative Opportunities to Broaden the Evidence Base. Heart Lung and Circulation,24(6):536-543.

Document type: Journal Article
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IRMA ID 75039815xPUB935
Title Northern Territory Perspectives on Heart Failure with Comorbidities - Understanding Trial Validity and Exploring Collaborative Opportunities to Broaden the Evidence Base
Author Iyngkaran, P.
Majoni, William
Cass, Alan
Sanders, Prashanthan
Ronco, C.
Brady, Stephen
Kangaharan, N.
Ilton, Marcus
Hare, D. L.
Thomas, Merlin C.
Journal Name Heart Lung and Circulation
Publication Date 2015
Volume Number 24
Issue Number 6
ISSN 1443-9506   (check CDU catalogue  open catalogue search in new window)
Scopus ID 2-s2.0-84929952114
Start Page 536
End Page 543
Total Pages 8
Place of Publication Australia
Publisher Elsevier Australia
Field of Research 1117 - Public Health and Health Services
HERDC Category C1 - Journal Article (DIISR)
Abstract Congestive Heart Failure (CHF) is an ambulatory care sensitive condition, associated with significant morbidity and mortality, rarely with cure. Outpatient based pharmacological management represents the main and most important aspect of care, and is usually lifelong. This narrative styled opinion review looks at the pharmacological agents recommended in the guidelines in context of the Northern Territory (NT) of Australia. We explore the concept of validity, a term used to describe the basis of standardising a particular trial or study and the population to which it is applicable. We aim to highlight the problems of the current guidelines based approach. We also present alternatives that could utilise the core principles from major trials, while incorporating regional considerations, which could benefit clients living in the NT and remote Australia.
Keywords Guidelines
Heart Failure
Indigenous Australians
Therapeutics
Remote
Rural
DOI http://dx.doi.org/10.1016/j.hlc.2014.12.007   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)
 
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Created: Tue, 26 Jul 2016, 12:52:58 CST