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Prevalence of depression and its associations with cardio-metabolic control in Aboriginal and Anglo-Celt patients with type 2 diabetes: The Fremantle Diabetes study Phase II

Davis, Timothy M. E., Hunt, Kerry, Bruce, David G., Starkstein, Sergio, Skinner, Timothy, McAullay, Daniel and Davis, Wendy A. (2015). Prevalence of depression and its associations with cardio-metabolic control in Aboriginal and Anglo-Celt patients with type 2 diabetes: The Fremantle Diabetes study Phase II. Diabetes Research and Clinical Practice,107(3):384-391.

Document type: Journal Article
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IRMA ID 84377429xPUB12
Title Prevalence of depression and its associations with cardio-metabolic control in Aboriginal and Anglo-Celt patients with type 2 diabetes: The Fremantle Diabetes study Phase II
Author Davis, Timothy M. E.
Hunt, Kerry
Bruce, David G.
Starkstein, Sergio
Skinner, Timothy
McAullay, Daniel
Davis, Wendy A.
Journal Name Diabetes Research and Clinical Practice
Publication Date 2015
Volume Number 107
Issue Number 3
ISSN 0168-8227   (check CDU catalogue  open catalogue search in new window)
Scopus ID 2-s2.0-84924205606
Start Page 384
End Page 391
Total Pages 8
Place of Publication Ireland
Publisher Elsevier Ireland Ltd.
Field of Research MEDICAL AND HEALTH SCIENCES
HERDC Category C1 - Journal Article (DIISR)
Abstract Aims
To determine the prevalence and associates of depression in Aboriginal and Anglo-Celt (AC) Australians with type 2 diabetes.

Methods
Community-based patients were screened using the Patient Health Questionnaire (PHQ-9) as part of detailed assessment. The prevalence of any current depression, major depression and antidepressant use by racial group was compared after adjustment for age, sex, educational attainment and marital status. Multiple logistic regression was used to determine associates of current depression.

Results
The 107 Aboriginal participants were younger (mean ± SD 54.3 ± 11.8 vs 67.2 ± 10.6 years), less often male (34.6% vs 50.9%) and married (39.3% vs 61.7%), and more likely to smoke (44.6% vs 8.1%) than the 793 AC subjects (P ≤ 0.002). Fifty-two Aboriginal (48.5%) and 772 AC participants (97.4%) completed the PHQ-9; these Aboriginals had similar socio-demographic, anthropometric and diabetes-related characteristics to those without PHQ-9 data. A quarter of the Aboriginals had current depression vs 10.6% of ACs (P = 0.16), 15.4% vs 4.1% had major depression (P = 0.029), and 68.8% vs 29.7% had untreated depression (P = 0.032). Compared with non-depressed participants, patients with current depression were younger and more likely to smoke, to be overweight/obese and to have worse glycaemic control (P ≤ 0.024). Significant independent associates of current depression were educational attainment (inversely), smoking status, body mass index and fasting plasma glucose in the AC group and alcohol use in the Aboriginal group.

Conclusions
Although prevalence of depression was not significantly increased in the Aboriginal patients, it was more likely to be major and untreated. Depression complicating type 2 diabetes is associated with adverse cardiovascular risk.
Keywords Type 2 diabetes
Depression
Aboriginal
Antidepressant treatment
Metabolic control
DOI http://dx.doi.org/10.1016/j.diabres.2014.12.014   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)
 
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