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Predictive indicators for Ross River virus infection in the Darwin area of tropical northern Australia, using long-term mosquito trapping data

Jacups, Susan P., Whelan, Peter I., Markey, Peter G., Cleland, Sam J., Williamson, Grant J. and Currie, Bart J. (2008). Predictive indicators for Ross River virus infection in the Darwin area of tropical northern Australia, using long-term mosquito trapping data. Tropical Medicine and International Health,13(7):943-952.

Document type: Journal Article

IRMA ID 79264104xPUB28
Title Predictive indicators for Ross River virus infection in the Darwin area of tropical northern Australia, using long-term mosquito trapping data
Author Jacups, Susan P.
Whelan, Peter I.
Markey, Peter G.
Cleland, Sam J.
Williamson, Grant J.
Currie, Bart J.
Journal Name Tropical Medicine and International Health
Publication Date 2008
Volume Number 13
Issue Number 7
ISSN 1360-2276   (check CDU catalogue  open catalogue search in new window)
Scopus ID 2-s2.0-44949123579
Start Page 943
End Page 952
Total Pages 10
Place of Publication UK
Publisher Wiley-Blackwell Publishing Ltd.
Field of Research 1117 - Public Health and Health Services
HERDC Category C1 - Journal Article (DEST)
Abstract OBJECTIVES: To describe the epidemiology of Ross River virus (RRV) infection in the endemic Darwin region of tropical northern Australia and to develop a predictive model for RRV infections.

METHODS: Analysis of laboratory confirmed cases of RRV infection between 01 January 1991 and 30 June 2006, together with climate, tidal and mosquito data collected weekly over the study period from 11 trap sites around Darwin. The epidemiology was described, correlations with various lag times were performed, followed by Poisson modelling to determine the best main effects model to predict RRV infection.

RESULTS: Ross River virus infection was reported equally in males and females in 1256 people over the 15.5 years. Average annual incidence was 113/100 000 people. Infections peaked in the 30-34 age-group for both sexes. Correlations revealed strong associations between monthly RRV infections and climatic variables and also each of the four implicated mosquito species populations. Three models were created to identify the best predictors of RRV infections for the Darwin area. The climate-only model included total rainfall, average daily minimum temperature and maximum tide. This model explained 44.3% deviance. Using vector-only variables, the best fit was obtained with average monthly trap numbers of Culex annulirostris, Aedes phaecasiatus, Aedes notoscriptus and Aedes vigilax. This model explained 59.5% deviance. The best global model included rainfall, minimum temperature and three mosquito species. This model explained 63.5% deviance, and predicted disease accurately.

CONCLUSIONS: We have produced a model that accurately predicts RRV infections throughout the year, in the Darwin region. Our model also indicates that predicted anthropogenic global climatic changes may result in an increase in RRV infections. Further research needs to target other high-risk areas elsewhere in tropical Australia to ascertain the best local climatic and vector predictive RRV infection models for each region. This methodology can also be tested for assessing utility of predictive models for other mosquito-borne diseases endemic to locations outside Australia.
Keywords arbovirus
Ross River virus
epidemiology
tropical
mosquito-borne disease
climate change
DOI http://dx.doi.org/10.1111/j.1365-3156.2008.02095.x   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)
 
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