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Diagnosis and treatment of invasive group A streptococcal infections

Steer, A. C., Curtis, N. and Carapetis, Jonathan R. (2008). Diagnosis and treatment of invasive group A streptococcal infections. Expert Opinion on Medical Diagnostics,2(3):289-301.

Document type: Journal Article

IRMA ID 83950043xPUB68
Title Diagnosis and treatment of invasive group A streptococcal infections
Author Steer, A. C.
Curtis, N.
Carapetis, Jonathan R.
Journal Name Expert Opinion on Medical Diagnostics
Publication Date 2008
Volume Number 2
Issue Number 3
ISSN 1753-0059   (check CDU catalogue  open catalogue search in new window)
Start Page 289
End Page 301
Total Pages 13
Place of Publication UK
Publisher Informa Healthcare
Field of Research 1116 - Medical Physiology
HERDC Category C1 - Journal Article (DEST)
Abstract Background: Invasive group A streptococcal infections are serious infections that carry a high mortality. Objective: The aim was to review current methods of diagnosis and treatment of invasive group A streptococcal infections as well as to provide background on the pathogenesis and epidemiology of these infections. Methods: The most recent literature regarding pathogenesis, epidemiology, diagnosis and treatment of invasive group A streptococcal infections is reviewed. Results/conclusion: The incidence of invasive group A streptococcal infections in industrialised countries is in the order of 3 per 100,000, whereas in developing countries available evidence suggests that the incidence is several-fold higher. Management of invasive group A streptococcal infections includes supportive care, surgical debridement of necrotic tissue, correct use of antibiotics, intravenous immunoglobulin and contact prophylaxis. Recent studies suggest that the early use of intravenous immunoglobulin may reduce the need for radical debridement of tissue in cases of necrotising fasciitis.
DOI http://dx.doi.org/10.1517/17530059.2.3.289   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)
 
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Created: Thu, 07 May 2009, 10:48:55 CST by Sarena Wegener