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Tuberculosis into the 2010s: Is the Glass Half Full?

Ralph, A., Anstey, Nicholas M. and Kelly, P. (2009). Tuberculosis into the 2010s: Is the Glass Half Full?. Clinical Infectious Diseases,49(4):574-583.

Document type: Journal Article

IRMA ID 10002xPUB29
Title Tuberculosis into the 2010s: Is the Glass Half Full?
Author Ralph, A.
Anstey, Nicholas M.
Kelly, P.
Journal Name Clinical Infectious Diseases
Publication Date 2009
Volume Number 49
Issue Number 4
ISSN 1537-6591   (check CDU catalogue open catalogue search in new window)
Scopus ID 2-s2.0-67651089506
Start Page 574
End Page 583
Total Pages 10
Place of Publication US
Publisher University of Chicago Press
HERDC Category C1 - Journal Article (DEST)
Abstract During the 16 years since the World Health Organization declared tuberculosis (TB) a global emergency, major new challenges have emerged—in particular the spread of extensively drug‐resistant (XDR)‐TB and its overlap with human immunodeficiency virus infection. However, during this period, we have also witnessed the creation of—and major commitments from—agencies dedicated to TB control, research, and funding, and tangible positive achievements have occurred; these include improvements in both new and existing TB diagnostics, a developmental pipeline of new candidate TB drugs, better treatment outcomes for multidrug‐resistant TB and XDR‐TB, heightened recognition of the importance of nosocomial transmission, and improved strategies to reduce mortality associated with concurrent human immunodeficiency virus infection and TB. We suggest updates to the 2006 International Standards of Tuberculosis Care to embrace these developments. The incorporation of these recent advances into optimized directly observed treatment, short course (DOTS), programs, in conjunction with more widespread deployment and enhanced political will, all provide grounds for improved control.
Keywords tuberculosis
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Created: Thu, 04 Mar 2010, 17:54:31 CST