Charles Darwin University

CDU eSpace
Institutional Repository

 
CDU Staff and Student only
 

Rotavirus and the indigenous children of the Australian outback: monovalent vaccine effective in a high-burden setting

Snelling, T., Schultz, R., Graham, J., Roseby, R., Barnes, G., Andrews, Ross M. and Carapetis, Jonathan R. (2009). Rotavirus and the indigenous children of the Australian outback: monovalent vaccine effective in a high-burden setting. Clinical Infectious Diseases,49(3):428-431.

Document type: Journal Article

IRMA ID 75039815xPUB182
Title Rotavirus and the indigenous children of the Australian outback: monovalent vaccine effective in a high-burden setting
Author Snelling, T.
Schultz, R.
Graham, J.
Roseby, R.
Barnes, G.
Andrews, Ross M.
Carapetis, Jonathan R.
Journal Name Clinical Infectious Diseases
Publication Date 2009
Volume Number 49
Issue Number 3
ISSN 1537-6591   (check CDU catalogue open catalogue search in new window)
Start Page 428
End Page 431
Total Pages 4
Place of Publication US
Publisher University of Chicago Press
HERDC Category C1 - Journal Article (DEST)
Abstract Indigenous children living in arid Central Australia experience frequent outbreaks of rotavirus gastroenteritis. A widespread outbreak of G9 rotavirus infection occurred several months after introduction of the RIX4414 rotavirus vaccine. We performed a retrospective case-control study to determine vaccine efficacy during the outbreak. Two doses provided an estimated vaccine efficacy of 77.7% (95% confidence interval, 40.2%-91.7%) against hospitalization for gastroenteritis. Vaccine efficacy was 84.5% (95% confidence interval, 23.4%-96.9%) against confirmed cases of rotavirus infection. Vaccination was effective in this high-burden setting.
DOI http://dx.doi.org/10.1086/600395   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)
 
Versions
Version Filter Type
Access Statistics: 38 Abstract Views  -  Detailed Statistics
Created: Thu, 18 Mar 2010, 20:11:27 CST by Sarena Wegener