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Meningitis and a febrile vomiting illness caused by echovirus type 4, Northern Territory, Australia

Markey, Peter G., Davis, Joshua S., Harnett, Gerry B., Williams, Simon H. and Speers, David J. (2010). Meningitis and a febrile vomiting illness caused by echovirus type 4, Northern Territory, Australia. Emerging Infectious Diseases,16(1):63-68.

Document type: Journal Article
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IRMA ID 81704288xPUB255
Title Meningitis and a febrile vomiting illness caused by echovirus type 4, Northern Territory, Australia
Author Markey, Peter G.
Davis, Joshua S.
Harnett, Gerry B.
Williams, Simon H.
Speers, David J.
Journal Name Emerging Infectious Diseases
Publication Date 2010
Volume Number 16
Issue Number 1
ISSN 1080-6040   (check CDU catalogue open catalogue search in new window)
Start Page 63
End Page 68
Total Pages 5
Place of Publication United States
Publisher U.S. Department of Health and Human Services, Centers for Disease Control and Prevention
HERDC Category C1 - Journal Article (DEST)
Abstract In July 2007, a cluster of meningitis cases caused by an echovirus 4 strain was detected in 1 indigenous community in the Top End of the Northern Territory of Australia. Illness was characterized by fever, vomiting, and headache. Over the next 4 months, additional cases of meningitis and the fever and vomiting syndrome emerged in other indigenous communities and subsequently in the major urban center of Darwin. We describe the epidemiology of 95 laboratory-confirmed meningitis cases and conclude that the epidemic fever and vomiting syndrome was caused by the same enterovirus. Nucleotide sequencing of the whole genome verified this enterovirus (AUS250G) as a strain of echovirus type 4. Viral protein 1 nucleotide sequencing demonstrated 96% homology with an echovirus 4 strain responsible for a large outbreak of meningitis in the Yanbian Prefecture of China in 1996.
DOI http://dx.doi.org/10.3201/eid1601.081519   (check subscription with CDU E-Gateway service for CDU Staff and Students  check subscription with CDU E-Gateway in new window)


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